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	Provedor de dados BJID (3) Autor Villegas,Maria Virginia (3) Blanco,Manuel Guzmán (1) Briceno,David Felipe (1) Furtado,Guilherme H (1) Gotuzzo,Eduardo (1) Guzmán-Blanco,Manuel (1) Labarca,Jaime A. (1) Nicolau,David P (1) Rossi,Flávia (1) Ruiz,Sory Jamil (1) Sifuentes-Osornio,Jose (1) Mais... Palavra-chave Drug resistance (2) Gram-negative bacteria (2) Bacterial (1) Bacterial resistance (1) Beta-lactamases (1) Carbapenems (1) Colombia (1) ESBL (1) Escherichia coli (1) Klebsiella (1) Latin America (1) Monte Carlo Method (1) Pharmacology (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2014 (1) 2011 (2) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Assessing the pharmacodynamic profile of intravenous antibiotics against prevalent Gram-negative organisms collected in Colombia BJID Villegas,Maria Virginia; Briceno,David Felipe; Ruiz,Sory Jamil; Furtado,Guilherme H; Nicolau,David P. OBJECTIVES: This study was designed to simulate standard and optimized dosing regimens for intravenous antibiotics against contemporary populations of Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa using MIC distribution data to determine which of the tested carbapenem regimens provided the greatest opportunity for obtaining maximal pharmacodynamic (PD) activity. METHODS: The isolates studied were obtained from the COMPACT-COLOMBIA surveillance program conducted between February and November 2009. Antimicrobial susceptibility testing was conducted by broth microdilution method according to the CLSI guidelines. Doripenem, imipenem-cilastatin, and meropenem, were the modeled antibiotics. A 5,000 patient Monte... Tipo: Info:eu-repo/semantics/article Palavras-chave: Drug resistance; Bacterial; Gram-negative bacteria; Monte Carlo Method; Colombia; Pharmacology. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500001 Extended spectrum β-lactamase producers among nosocomial Enterobacteriaceae in Latin America BJID Guzmán-Blanco,Manuel; Labarca,Jaime A.; Villegas,Maria Virginia; Gotuzzo,Eduardo. To review the epidemiology of nosocomial extended spectrum β-lactamase-producing Enterobacteriaceae in Latin America, a systematic search of the biomedical literature (PubMed) was performed for articles published since 2005. Rates of nosocomial infections caused by extended spectrum β-lactamase-producing Enterobacteriaceae in Latin America have increased since 2005. Up to 32% of Escherichia coli and up to 58% of Klebsiella pneumoniae isolates are extended spectrum β-lactamase-positive, rates that are higher than in other world regions. From a region-wide perspective, 11-25% of E. coli isolates and 45-53% of K. pneumoniae isolates were nonsusceptible to third-generation cephalosporins. At the country level, there was a wide range in Enterobacteriaceae... Tipo: Info:eu-repo/semantics/article Palavras-chave: Escherichia coli; Klebsiella; Latin America; Bacterial resistance. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400421 Increasing prevalence of extended-spectrum-betalactamase among Gram-negative bacilli in Latin America: 2008 update from the Study for Monitoring Antimicrobial Resistance Trends (SMART) BJID Villegas,Maria Virginia; Blanco,Manuel Guzmán; Sifuentes-Osornio,Jose; Rossi,Flávia. OBJECTIVES: This analysis of the Study for Monitoring Antimicrobial Resistance Trends (SMART) evaluated the susceptibility patterns of Enterobacteriaceae in Latin America in 2008, with emphasis on susceptibility trends of E. coli and K. pneumoniae. METHODS: Clinical isolates were recovered from intra-abdominal infections (IAI) from 23 centers in 10 Latin American countries. Isolates were sent to a central laboratory for confirmation of identification, antimicrobial susceptibility and ESBL testing, following the Clinical Laboratory Standards Institute (CLSI) guidelines. RESULTS: Of 1,003 Gram-negative bacilli collected from intra-abdominal infections, E. coli and K. pneumoniae were the most commonly isolated organisms, and 26.8% of E. coli and 37.7% of K.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Carbapenems; Beta-lactamases; Gram-negative bacteria; Drug resistance; ESBL. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100007 Registros recuperados: 3 Primeira ... 1 ... Última

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